Evaluation of Two‐Test Serodiagnostic Method for Early Lyme Disease in Clinical Practice

Advances in Serodiagnostic Testing for Lyme Disease Are at Hand.

The cause of Lyme disease, Borrelia burgdorferi, was discovered in 1983. A 2-tiered testing protocol was established for serodiagnosis in 1994, involving an enzyme immunoassay (EIA) or indirect fluorescence antibody, followed (if reactive) by immunoglobulin M and immunoglobulin G Western immunoblots. These assays were prepared from whole-cell cultured B. burgdorferi, lacking key in vivo express...

Improved serodiagnostic testing for Lyme disease: results of a multicenter serologic evaluation.

The diverse clinical manifestations of Lyme disease (1-3) have led to frequent confusion in clinical diagnosis, a confusion compounded by problems in the accuracy and precision of diagnostic serologic tests (4-11) and the difficulty of isolating the causative organism (12-14), Borrelia burgdorferi. In 1990, more than 20 commercially prepared serologic test kits for Lyme disease were being sold ...

Comparative Evaluation of Serodiagnostic Techniques in Cystic Hydatid Disease

hazard evaluation of incinerators in mobin petrochemical company using hazop method

چکیده ندارد.

Early Lyme disease – current clinical and epidemiological aspects in Braşov

Background Lyme disease, endemic in Europe, North America and Asia, is caused by the Borrelia burgdorferi bacteria. In the absence of a correct diagnosis and an early and appropriate treatment, it evolves in 3 stages: early localized stage (erythema migrans – present in the majority but not in all the patients – fever, fatigue, myalgia, headache, neck stiffness); early disseminated stage (secon...